VHA-19 IS ESSENTIAL IN CAENORHABDITIS ELEGANS OOCYTES FOR EMBRYOGENESIS AND IS INVOLVED IN TRAFFICKING IN OOCYTES.

VHA-19 is essential in Caenorhabditis elegans oocytes for embryogenesis and is involved in trafficking in oocytes.

There is an urgent need to develop new drugs against parasitic nematodes, which are a significant burden on human health and agriculture.Information about the function of hcpch cat vaccine essential nematode-specific genes provides insight to key nematode-specific processes that could be targeted with drugs.We have characterized the function of a n

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Ethical and social implications of approaching death prediction in humans - when the biology of ageing meets existential issues

Abstract Background The discovery of biomarkers of ageing has led to the development of predictors of impending natural death and has paved the way for personalised estimation of the risk of death in the general population.This study intends to identify the ethical resources available to approach the idea of a long-lasting dying process and conside

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The Challenge Non-Typhoidal Salmonella (CHANTS) Consortium: Development of a non-typhoidal Salmonella controlled human infection model: Report from a consultation group workshop, 05 July 2022, London, UK [version 2; peer review: 2 approved]

Invasive non-typhoidal Salmonella disease (iNTS) is a major cause of morbidity and mortality globally, particularly as a cause of bloodstream infection in children and immunocompromised adults in sub-Saharan Africa.Vaccines to prevent non-typhoidal Salmonella (NTS) would represent a valuable public health tool in this setting to avert cases and pre

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